How far can we simplify in vitro diagnostics for grass pollen allergy?: A study with 17 whole pollen extracts and purified natural and recombinant major allergens.

@article{Ree1998HowFC,
  title={How far can we simplify in vitro diagnostics for grass pollen allergy?: A study with 17 whole pollen extracts and purified natural and recombinant major allergens.},
  author={Ronald van Ree and W Astrid van Leeuwen and Rob C Aalberse},
  journal={The Journal of allergy and clinical immunology},
  year={1998},
  volume={102 2},
  pages={
          184-90
        }
}
BACKGROUND Current diagnostics for grass pollen allergy are composed of mixtures of pollen of different grass species. Their complex composition hampers accurate standardization. OBJECTIVE The aim of the study was to investigate whether mixtures of grass pollen extracts can be replaced by a single pollen species and whether a single pollen species can be replaced by a limited number of purified natural or recombinant major allergens. METHODS Sera (n = 800) were selected on the basis of a… CONTINUE READING

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