How electron cryotomography is opening a new window onto prokaryotic ultrastructure.

@article{Jensen2007HowEC,
  title={How electron cryotomography is opening a new window onto prokaryotic ultrastructure.},
  author={Grant J. Jensen and Ariane Briegel},
  journal={Current opinion in structural biology},
  year={2007},
  volume={17 2},
  pages={260-7}
}
Electron cryotomography is an emerging technology that enables thin samples, including small intact prokaryotic cells, to be imaged in three dimensions in a near-native 'frozen-hydrated' state to a resolution sufficient to recognize very large macromolecular complexes in situ. Following years of visionary technology development by a few key pioneers, several laboratories are now using the technique to produce biological results of major significance in the field of prokaryotic ultrastructure… CONTINUE READING

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