How does the timing of antiretroviral therapy initiation in acute infection affect HIV reservoirs?

PURPOSE OF REVIEW The long-lived viral reservoir is a major obstacle to achieving a cure for HIV. Therapeutic strategies, such as early antiretroviral therapy (ART), may be a prerequisite to achieving long-term control of viral replication upon ART withdrawal. RECENT FINDINGS HIV persistence is established early in acute HIV infection (AHI) with infection… CONTINUE READING