How does high DHA fish oil affect health? A systematic review of evidence

  title={How does high DHA fish oil affect health? A systematic review of evidence},
  author={Samaneh Ghasemi Fard and Fenglei Wang and Andrew J Sinclair and Glenn Elliott and Giovanni M. Turchini},
  journal={Critical Reviews in Food Science and Nutrition},
  pages={1684 - 1727}
ABSTRACT The health benefits of fish oil, and its omega-3 long chain polyunsaturated fatty acid content, have attracted much scientific attention in the last four decades. Fish oils that contain higher amounts of eicosapentaenoic acid (EPA; 20:5n-3) than docosahexaenoic acid (DHA; 22:6n-3), in a distinctive ratio of 18/12, are typically the most abundantly available and are commonly studied. Although the two fatty acids have traditionally been considered together, as though they were one entity… 
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Evidence from epidemiological studies and RCTs will be reviewed, and recommendations reflecting the current state of knowledge will be made with regard to both fish consumption and omega-3 fatty acid (plant- and marine-derived) supplementation.
Effects of fish-oil supplementation on myocardial fatty acids in humans.
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  • S. Dyall
  • Biology
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  • 2015
With a greater understanding of the individual roles of EPA, DPA and DHA in brain health and repair it is hoped that appropriate dietary recommendations can be established and therapeutic interventions can be more targeted and refined.
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