How does endothelial cell injury start? The role of endothelin in systemic sclerosis

@article{Abraham2007HowDE,
  title={How does endothelial cell injury start? The role of endothelin in systemic sclerosis},
  author={David J. Abraham and Oliver Distler},
  journal={Arthritis Research & Therapy},
  year={2007},
  volume={9},
  pages={S2 - S2}
}
A considerable amount of research time has been invested in studies aimed at elucidating pathogenic processes in systemic sclerosis (SSc). Despite this, major challenges for biomedical science remain, such as identification of the key factors that determine susceptibility to SSc, and elucidation of the precise nature of the initiating event that causes endothelial cell injury and ultimately brings about the biological cascade(s) that lead to the pathologic vascular changes. Involved factors are… CONTINUE READING
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