How do tissues respond to damage at the cellular level? The role of cytokines in irradiated tissues.

@article{BarcellosHoff1998HowDT,
  title={How do tissues respond to damage at the cellular level? The role of cytokines in irradiated tissues.},
  author={Mary Helen Barcellos-Hoff},
  journal={Radiation research},
  year={1998},
  volume={150 5 Suppl},
  pages={S109-20}
}
The capacity of ionizing radiation to affect tissue function, control tumor growth and elicit pathological sequelae has been attributed in great part to its effects on cellular DNA, which, as the transmitter of genetic information, can both register damage and perpetuate it. Nonetheless, multicellular organisms function as the result of the cooperation of many cell types. What then occurs when individual cells are damaged by ionizing radiation? Is tissue response a sum of cellular effects such… CONTINUE READING

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