How do heterogametic females survive without gene dosage compensation?

  title={How do heterogametic females survive without gene dosage compensation?},
  author={H. Sharat Chandra},
  journal={Journal of Genetics},
When the male is the heterogametic sex (XX♀-XY♂ or XX♀-XO♂), as inDrosophila, orthopteran insects, mammals andCaenorhabditis elegans, X-linked genes are subject to dosage compensation: the single X in the male is functionally equivalent to the two Xs in the female. However, when the female is heterogametic (ZZ♂-ZW♀), as in birds, butterflies and moths, Z-linked genes are apparently not dosage-compensated. This difference between X-linked and Z-linked genes raises fundamental questions about the… CONTINUE READING


Publications referenced by this paper.
Showing 1-10 of 54 references

Dosage compensation and sex chromatin in non-mammals

A. G. Cock
Genet. Res • 1964
View 5 Excerpts
Highly Influenced

Role of the esc+ gene product in ensuring the selective expression of segment-specific homeotic genes in Drosophila.

Journal of embryology and experimental morphology • 1983
View 3 Excerpts
Highly Influenced

Hemolymph polymorphism in a moth and the nature of sex-controlled inheritance

G. Stehr
Evolution • 1959
View 4 Excerpts
Highly Influenced

Dominant maternaleffect mutations causing embryonic lethality in Caenorhabditis elegans

J. ManseauL., T Sctmpbach
Genetics • 1990

Dosage requirements of ulzrabithorax and bithoraxoid in the determination of segment identity of Drosophila mehmogaster

S M.
Lepidoptera. Adv. Genet • 1990
View 1 Excerpt

Reciprocal effect of hyper- and

T R.Strecker, S R.Halsell, W W.Fisher, H D.Lipshitz

Reciprocal effect of hyperand hypoactivity in the Drosophila pattern gene torso

G Struhl
Science • 1989

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