How did glycogen structure evolve to satisfy the requirement for rapid mobilization of glucose? A problem of physical constraints in structure building

Abstract

Optimization of molecular design in cellular metabolism is a necessary condition for guaranteeing a good structure-function relationship. We have studied this feature in the design of glycogen by means of the mathematical model previously presented that describes glycogen structure and its optimization function [Meléndez-Hevia et al. (1993), Biochem J 295… (More)
DOI: 10.1007/PL00006249

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