How could a cell regulate its internal Pi concentration?

  title={How could a cell regulate its internal Pi concentration?},
  author={Graham J. Kemp and Alan Bevington},
  journal={Biochemical Society transactions},
  volume={17 6},
Many mammalian cells appear to regulate their internal P, concentration against changes in extracellular P, [ l] . Here we describe a theoretical model which shows how this may be partly accounted for by an active PI influx into the cell, balanced by a passive PI efflux. In the absence of active transport, Pi distributes passively in both directions across the plasma membrane so that the ratio ( R ) of intracellular concentration ( Cz) to extracellular PI concentration (C,) is equal to the… CONTINUE READING