How cells respond to interferons.

@article{Stark1998HowCR,
  title={How cells respond to interferons.},
  author={George R. Stark and Ian M. Kerr and Bryan R. G. Williams and Robert H. Silverman and Robert D. Schreiber},
  journal={Annual review of biochemistry},
  year={1998},
  volume={67},
  pages={
          227-64
        }
}
Interferons play key roles in mediating antiviral and antigrowth responses and in modulating immune response. The main signaling pathways are rapid and direct. They involve tyrosine phosphorylation and activation of signal transducers and activators of transcription factors by Janus tyrosine kinases at the cell membrane, followed by release of signal transducers and activators of transcription and their migration to the nucleus, where they induce the expression of the many gene products that… 

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