How cells channel their stress: Interplay between Piezo1 and the cytoskeleton.

  title={How cells channel their stress: Interplay between Piezo1 and the cytoskeleton.},
  author={Jamison L. Nourse and Medha M. Pathak},
  journal={Seminars in cell & developmental biology},
Cells constantly encounter mechanical stimuli in their environment, such as dynamic forces and mechanical features of the extracellular matrix. These mechanical cues are transduced into biochemical signals, and integrated with genetic and chemical signals to modulate diverse physiological processes. Cells also actively generate forces to internally transport cargo, to explore the physical properties of their environment and to spatially position themselves and other cells during development… CONTINUE READING

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