How can we help patients with refractory chronic graft versus host disease- single centre experience.

@article{Rzepecki2007HowCW,
  title={How can we help patients with refractory chronic graft versus host disease- single centre experience.},
  author={Piotr Rzepecki and Justyna Barzal and Tomasz Sarosiek and Sylwia Oborska and Cezary A. Szczylik},
  journal={Neoplasma},
  year={2007},
  volume={54 5},
  pages={431-6}
}
Chronic graft-versus-host disease (cGVHD) is a major cause of morbidity and mortality in long-term survivors of allogeneic haematopoietic stem cell transplantation (alloHSCT). Ocular involvement as well as dermal sclerosis, joint contractures and pathological changes in oral cavity are often refractory to treatment. This kind of patients require complex aggressive immunosuppressive therapy. We are still waiting for drugs against cGVHD, characterized by decreased infectious complications… CONTINUE READING