How best to consider the structure and function of the pedunculopontine tegmental nucleus: Evidence from animal studies

  title={How best to consider the structure and function of the pedunculopontine tegmental nucleus: Evidence from animal studies},
  author={P. Winn},
  journal={Journal of the Neurological Sciences},
  • P. Winn
  • Published 2006
  • Psychology, Medicine
  • Journal of the Neurological Sciences
  • This review presents the hypothesis that the best way to consider the pedunculopontine tegmental nucleus is by analogy with the substantia nigra. The substantia nigra contains two main compartments: the pars compacta and the pars reticulata. The former contains dopamine neurons that project widely within the basal ganglia while the latter is in receipt of corticostriatal output. Similarly, the PPTg contains the Ch5 acetylcholine containing neurons that project to the thalamus and… CONTINUE READING
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