How an increased intake of alpha-tocopherol can suppress the bioavailability of gamma-tocopherol.

@article{Wolf2006HowAI,
  title={How an increased intake of alpha-tocopherol can suppress the bioavailability of gamma-tocopherol.},
  author={G. Wolf},
  journal={Nutrition reviews},
  year={2006},
  volume={64 6},
  pages={
          295-9
        }
}
  • G. Wolf
  • Published 2006
  • Chemistry, Medicine
  • Nutrition reviews
  • alpha-Tocopherol is the only form of vitamin E in vitamin supplements, whereas gamma-tocopherol is the predominant form of vitamin E in the US diet. gamma-Tocopherol has beneficial properties as an anti-inflammatory and possibly anti-atherogenic and anticancer agent. Excess a-tocopherol taken in supplements causes a reduction of gamma-tocopherol concentration in plasma. The biochemical mechanism of this effect, which is important to human nutrition, has recently been elucidated. 
    72 Citations

    Figures and Topics from this paper

    A MINI-OVERVIEW OF VITAMIN
    • PDF
    δ-Tocopherol Is More Active than α- or γ-Tocopherol in Inhibiting Lung Tumorigenesis In Vivo
    • 78
    • PDF

    References

    SHOWING 1-10 OF 35 REFERENCES
    gamma-tocopherol, the major form of vitamin E in the US diet, deserves more attention.
    • 668
    • Highly Influential
    • PDF
    Failure of vitamin E in clinical trials: is gamma-tocopherol the answer?
    • 48
    • PDF
    Oral α-Tocopherol Supplements Decrease Plasma γ-Tocopherol Levels in Humans
    • 241
    • Highly Influential
    Preferential incorporation of alpha-tocopherol vs gamma-tocopherol in human lipoproteins.
    • 273
    Cigarette smoke alters human vitamin E requirements.
    • 44
    • PDF
    Alpha-tocopherol metabolism is abnormal in scavenger receptor class B type I (SR-BI)-deficient mice.
    • 174
    • PDF