How affected is oxygen metabolism in DWI lesions?: A combined acute stroke PET-MR study

@article{Guadagno2006HowAI,
  title={How affected is oxygen metabolism in DWI lesions?: A combined acute stroke PET-MR study},
  author={Joseph V Guadagno and Elizabeth A. Warburton and P. Simon Jones and Diana J. Day and Franklin I. Aigbirhio and Tim D. Fryer and Sally Harding and Christopher J Price and Hadrian A. L. Green and Olivier Barret and Jonathan H. Gillard and Jean-Claude Baron},
  journal={Neurology},
  year={2006},
  volume={67},
  pages={824-829}
}
  • Joseph V Guadagno, Elizabeth A. Warburton, +9 authors Jean-Claude Baron
  • Published in Neurology 2006
  • Medicine
  • Objective:To use back-to-back diffusion-weighted imaging (DWI) and PET to obtain quantitative measures of the cerebral metabolic rate of oxygen (CMRO2) within DWI lesions, and to assess the perfusion-metabolism coupling status by measuring the cerebral blood flow and the oxygen extraction fraction within DWI lesions. Methods:Six prospectively recruited acute carotid-territory stroke patients completed the imaging protocol, which was commenced 7 to 21 hours from onset and combined DWI derived… CONTINUE READING

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