How Retroviruses Escape the Nonsense-Mediated mRNA Decay.

@article{Mocquet2015HowRE,
  title={How Retroviruses Escape the Nonsense-Mediated mRNA Decay.},
  author={Vincent Mocquet and S{\'e}bastien Durand and Pierre Jalinot},
  journal={AIDS research and human retroviruses},
  year={2015},
  volume={31 10},
  pages={948-58}
}
Many posttranscriptional processes are known to regulate gene expression and some of them can act as an antiviral barrier. The nonsense-mediated mRNA decay (NMD) was first identified as an mRNA quality control pathway that triggers rapid decay of mRNA containing premature stop codons due to mutations. NMD is now considered as a general posttranscriptional regulation pathway controlling the expression of a large set of cellular genes. In addition to premature stop codons, many other features… CONTINUE READING
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