How Low Should You Go: Novel Device for Nail Trephination

@article{Ciocon2006HowLS,
  title={How Low Should You Go: Novel Device for Nail Trephination},
  author={David H. Ciocon and Thiruvallur R. Gowrishankar and Terry O. Herndon and Alexa B Kimball},
  journal={Dermatologic Surgery},
  year={2006},
  volume={32},
  pages={828–833}
}
BACKGROUND The most commonly used treatment for subungual hematomas is nail trephination, a technique that is not standardized and that poorly controls for trephination depth. OBJECTIVE The objective was to test the safety and tolerance of a new device for nail trephination that uses innovative “mesoscission” or microcutting technology to create holes of specific depths in the nail plate without penetrating the nail bed. MATERIALS AND METHODS Fourteen adult subjects with healthy toenails had… 
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13 Citations
Background Citations
4
Methods Citations
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Results Citations
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13 Citations

Citation Type

Citation Type

Controlled nail trephination for subungual hematoma.
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TLDR
Three cases of toenail onychomycosis treated topical terbinafine 1% solution using controlled micro-penetration of the nail using a novel intelligent nail drill system which is able to drill nail plate without penetrating the delicate nail bed beneath are presented.
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The nail plate is a thick, tightly bound structure that protects the underlying nail bed from water loss, physical abrasion and infections. Despite its barrier properties, organisms are capable of…
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Comparative analysis of available treatment modalities for onychomycosis has been provided with pros and cons of each alternatives, and ongoing research about the application of biological materials such as modified cationic antimicrobial peptides, plant-derived proteins, and synthetic antimacterial peptidomimetics have also been explored.
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TLDR
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TLDR
This is the first systematic critique encompassing the detailed aspects of transungual drug delivery, a promising avenue for researchers to develop novel formulations, augmenting pharmaceutical industries to commercialize the products for nail disorders.
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  • 2010
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The topical therapy of nail diseases, especially of onychomycosis, and to a smaller extent, of nail psoriasis, is desirable to avoid the side effects associated with their systemic therapy, to…
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