How I treat paediatric relapsed acute myeloid leukaemia.

  title={How I treat paediatric relapsed acute myeloid leukaemia.},
  author={Gertjan J L Kaspers},
  journal={British journal of haematology},
  volume={166 5},
The prognosis of paediatric acute myeloid leukaemia (AML) has improved significantly over the recent decades, but still about one-third of patients relapse. These patients have a relatively poor prognosis, with a probability of long-term survival from relapse of about 35%. This can only be achieved with very intensive chemotherapy and, usually, allogeneic stem cell transplantation, leading to very significant toxicity and even treatment-related mortality. Major improvements in the treatment of… CONTINUE READING