How Does Fat Transition from White to Beige?

  title={How Does Fat Transition from White to Beige?},
  author={Marc L Reitman},
  journal={Cell metabolism},
  volume={26 1},
Fischer et al. (2017) recently reported that interleukin-4 (IL-4) does not increase adipose thermogenesis and that activated macrophages do not synthesize catecholamines. These findings are unexpected because IL-4 activation of macrophages has been proposed to have a pivotal role in cold-induced thermogenesis by stimulating macrophage catecholamine production to recruit thermogenic beige or brite fat. 
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