How Do Microbial Pathogens Make CENs?

Abstract

In a variety of pathogens, drug resistance and aneuploidy are intimately associated. Anueploidy is believed to alter the dosage of certain genes that can impart drug resistance. Generation of a new chromosome by duplication of chromosome segments followed by telomere addition in a pathogenic yeast Candida glabrata [1] and isochromosome formation by breakage… (More)
DOI: 10.1371/journal.ppat.1002463

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Cite this paper

@inproceedings{Sanyal2012HowDM, title={How Do Microbial Pathogens Make CENs?}, author={Kaustuv Sanyal}, booktitle={PLoS pathogens}, year={2012} }