Household survey of dengue infection in central Brazil: spatial point pattern analysis and risk factors assessment.


Urban dengue fever is now considered a major public health threat in most American countries. A household survey was conducted in the city of Goiania in central Brazil in 2001 to assess prevalence of dengue infection and individual and area-based risk factors. Spatial point pattern analysis was performed using the dual Kernel method. A total of 1,610 households were surveyed; 1,585 individuals more than five years old had blood and data collected. Sera were tested for IgM/IgG antibodies by an enzyme-linked immunoassay. Area-based indicators derived from census data were linked to geocoded residential address. The seroprevalence of dengue was 29.5% and the estimate prevalence surface reached 50% in the outskirts areas. The risk of infection was significantly associated with older age (P < 0.01), low education (odds ratio [OR] = 3.45, 95% confidence interval [CI] = 1.82-6.55), and low income (OR = 1.32, 95% CI = 1.02-1.71) in multivariate analysis. This study highlighted the heterogeneity of dengue transmission within the city and can assist in spatial targeting control interventions.

Citations per Year

93 Citations

Semantic Scholar estimates that this publication has 93 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Siqueira2004HouseholdSO, title={Household survey of dengue infection in central Brazil: spatial point pattern analysis and risk factors assessment.}, author={Jo{\~a}o Bosco Siqueira and Celina Maria Turchi Martelli and Ivan J Maciel and Renato Maur{\'i}cio de Oliveira and Maria Gil Ribeiro and Fl{\'u}via P Amorim and Bruno Moreira and Divina das D{\^o}res de Paula Cardoso and Wayner Vieira de Souza and Ana L{\'u}cia S. S. Andrade}, journal={The American journal of tropical medicine and hygiene}, year={2004}, volume={71 5}, pages={646-51} }