Hot Brains: Manipulating Body Heat to Save the Brain

@article{Raju2006HotBM,
  title={Hot Brains: Manipulating Body Heat to Save the Brain},
  author={Tonse N. K. Raju},
  journal={Pediatrics},
  year={2006},
  volume={117},
  pages={e320 - e321}
}
  • T. Raju
  • Published 1 February 2006
  • Medicine
  • Pediatrics
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References

SHOWING 1-10 OF 13 REFERENCES
A History of Psychiatry: From the Era of the Asylum to the Age of Prozac
TLDR
This biography is informative and com prehensive in its coverage of Jung's personal and public life, however, it emphasises his significance today as guru of New Age interest in Eastern thought, the paranormal and astrology, rather than recognising his place in the contemporary psychoanalytic and psychotherapeutic world. Expand
Julius Wagner - Jauregg : 1927
  • Nobel Chronicles : A Handbook of Nobel Prizes in Physiology or Medicine
  • 2002
Nobel Chronicles: A Handbook of Nobel Prizes in Physiology or Medicine
  • Bloomington, IN: 1st Books Library;
  • 2002
Nobel Chronicles: A Handbook of Nobel Prizes in Physiology or Medicine
  • 1st Books Library
  • 2002
Nobel Chronicles: A Handbook of Nobel Prizes in Physiology or Medicine. Bloomington, IN: 1st Books Library
  • Nobel Chronicles: A Handbook of Nobel Prizes in Physiology or Medicine. Bloomington, IN: 1st Books Library
  • 2002
Julius Wagner-Jauregg: 1927
  • Magill FN, ed. Nobel Prize Winners Physiology or Medicine
  • 1991
U ¨ ber die Einwirkung der Malaria auf die progressive Paralyse. Psychiatrisch-neurologische Wochenschrift
  • U ¨ ber die Einwirkung der Malaria auf die progressive Paralyse. Psychiatrisch-neurologische Wochenschrift
  • 1919
Ü ber die Einwirkung der Malaria auf die progressive Paralyse. Psychiatrisch-neurologische Wochenschrift
  • 1919
...
1
2
...