Host susceptibility to the attaching and effacing bacterial pathogen Citrobacter rodentium.

@article{Vallance2003HostST,
  title={Host susceptibility to the attaching and effacing bacterial pathogen Citrobacter rodentium.},
  author={Bruce A Vallance and Wanyin Deng and Kevan Jacobson and Brett B. Finlay},
  journal={Infection and immunity},
  year={2003},
  volume={71 6},
  pages={3443-53}
}
Many studies have shown that genetic susceptibility plays a key role in determining whether bacterial pathogens successfully infect and cause disease in potential hosts. Surprisingly, whether host genetics influence the pathogenesis of attaching and effacing (A/E) bacteria such as enteropathogenic and enterohemorrhagic Escherichia coli has not been examined. To address this issue, we infected various mouse strains with Citrobacter rodentium, a member of the A/E pathogen family. Of the strains… CONTINUE READING

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