Host responses in mediating sepsis and adult respiratory distress syndrome.

  title={Host responses in mediating sepsis and adult respiratory distress syndrome.},
  author={Robert M. Strieter and Joseph Pedulla Lynch and Mahaboob Basha and Theodore J Standiford and Keita Kasahara and Steven L. Kunkel},
  journal={Seminars in respiratory infections},
  volume={5 3},
Despite significant advances in intensive care unit technology and mechanical ventilatory support, mortality due to adult respiratory distress syndrome (ARDS) or multiorgan failure (MOF) has not changed significantly within the past two decades. The key to improving survival requires understanding and modifying (or eliminating) factors that may initiate (or modulate) these syndromes. Infection, and the host responses to infection, are major etiological factors responsible for the induction and… CONTINUE READING


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