Host range factor 1 from Lymantria dispar Nucleopolyhedrovirus (NPV) is an essential viral factor required for productive infection of NPVs in IPLB-Ld652Y cells derived from L. dispar.

@article{Ishikawa2004HostRF,
  title={Host range factor 1 from Lymantria dispar Nucleopolyhedrovirus (NPV) is an essential viral factor required for productive infection of NPVs in IPLB-Ld652Y cells derived from L. dispar.},
  author={Hiroki Ishikawa and Motoko Ikeda and Cristiano A. Felipe Alves and Suzanne M. Thiem and Michihiro Kobayashi},
  journal={Journal of virology},
  year={2004},
  volume={78 22},
  pages={
          12703-8
        }
}
Host range factor 1 (HRF-1) of Lymantria dispar multinucleocapsid nucleopolyhedrovirus promotes Autographa californica MNPV replication in nonpermissive Ld652Y cells derived from L. dispar. Here we demonstrate that restricted Hyphantria cunea NPV replication in Ld652Y cells was not due to apoptosis but was likely due to global protein synthesis arrest that could be restored by HRF-1. Our data also showed that HRF-1 promoted the production of progeny virions for two other baculoviruses, Bombyx… CONTINUE READING

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Characterization of FIG. 4. Replication of five different NPVs in HRF-1-expressing Ld652Y cells

C. A. Felipe Alves, M. Ikeda, M. Kobayashi
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Identification and Characterization of Hyphantria cunea Nucleopolyhedrovirus Homologous Repeated Regions

Cristiano A. Felipe Alves, Motoko Ikeda, Michihiro Kobayashi
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