Host range and oncogenicity studies of the murine myeloma MOPC-315 type-C retrovirus.

@article{Gazit1981HostRA,
  title={Host range and oncogenicity studies of the murine myeloma MOPC-315 type-C retrovirus.},
  author={Arnona Gazit and D Guthmann and Abraham Yaniv},
  journal={International journal of cancer},
  year={1981},
  volume={27 3},
  pages={335-40}
}
The biological features of an endogenous type-C RNA tumor virus released by the murine plasmacytoma MOPC-315 were determined. The virus was found to be pure ecotropic and, according to its capability to infect both NIH/3T3 and BALB/3T3 cells, it was established as an NB tropic virus. This tropism became more pronounced as a consequence of multiple passage in balb/3T3 cells. In view of the ability of myeloma viruses to efficiently infect BALB/c cells, their possible role in myeloma induction is… CONTINUE READING