Host-microbial interactions in childhood atopy: toll-like receptor 4 (TLR4), CD14, and fecal Escherichia coli.

@article{Penders2010HostmicrobialII,
  title={Host-microbial interactions in childhood atopy: toll-like receptor 4 (TLR4), CD14, and fecal Escherichia coli.},
  author={John Penders and Carel Thijs and Monique Mommers and Ellen E. Stobberingh and Edward Dompeling and Naomi E. Reijmerink and Piet A van den Brandt and M Kerkhof and Gerard H Koppelman and Dirkje S Postma},
  journal={The Journal of allergy and clinical immunology},
  year={2010},
  volume={125 1},
  pages={231-6.e1-5}
}
BACKGROUND Perturbations in the gut microbiota have been linked to atopic diseases. However, the development of atopic diseases depends not only on environmental factors (like microbial stimulation) but also on genetic factors. It is likely that particularly gene-environmental interactions in early life determine the development of atopy. OBJECTIVE We… CONTINUE READING