Host lung gene expression patterns predict infectious etiology in a mouse model of pneumonia

@inproceedings{Evans2010HostLG,
  title={Host lung gene expression patterns predict infectious etiology in a mouse model of pneumonia},
  author={Scott E Evans and Michael J. Tuvim and Jiexin Zhang and Derek T. Larson and C{\'e}sar de Carvalho Garcia and Sylvia Martinez Pro and Kevin R. Coombes and Burton F Dickey},
  booktitle={Respiratory research},
  year={2010}
}
BACKGROUND Lower respiratory tract infections continue to exact unacceptable worldwide mortality, often because the infecting pathogen cannot be identified. The respiratory epithelia provide protection from pneumonias through organism-specific generation of antimicrobial products, offering potential insight into the identity of infecting pathogens. This study assesses the capacity of the host gene expression response to infection to predict the presence and identity of lower respiratory… CONTINUE READING

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Stimulation of lung innate immunity protects mice broadly against bacterial and fungal pneumonia

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  • Am J Respir Cell Molec Biol
  • 2010
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