Host immunosuppression following orthotopic bowel allotransplantation in rats using low-dose cyclosporine.

Abstract

This study shows that Le rats bearing total bowel allografts treated with CyA (5 mg/kg for 14 days) demonstrated within one month immunological unresponsiveness to donor and third-party alloantigens as determined by MLR responses. Assays performed in long-term survivors (greater than 100 days) showed a continued depressed MLR response to antigen-specific… (More)

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Cite this paper

@article{Grogan1991HostIF, title={Host immunosuppression following orthotopic bowel allotransplantation in rats using low-dose cyclosporine.}, author={Jared Grogan and R Shimazu and Yasushi Masaki and Seshadri Raju}, journal={Transplantation proceedings}, year={1991}, volume={23 1 Pt 1}, pages={870-2} }