Host-guided migration allows targeted introduction of neurons into the embryonic brain

@article{Bruestle1995HostguidedMA,
  title={Host-guided migration allows targeted introduction of neurons into the embryonic brain},
  author={Oliver Bruestle and Uwe Maskos and Ronald D. G. McKay},
  journal={Neuron},
  year={1995},
  volume={15},
  pages={1275-1285}
}
The stereotyped positions occupied by individual classes of neurons are a fundamental characteristic of CNS cytoarchitecture. To study the regulation of neuronal positioning, we injected genetically labeled neural precursors derived from dorsal and ventral mouse forebrain into the telencephalic vesicles of embryonic rats. Cells from both areas were found to participate in the generation of telencephalic, diencephalic, and mesencephalic brain regions. Donor-derived neurons populated the host… CONTINUE READING

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