Host genetics determine susceptibility to avian influenza infection and transmission dynamics

@inproceedings{RuizHernandez2016HostGD,
  title={Host genetics determine susceptibility to avian influenza infection and transmission dynamics},
  author={Raul Ruiz-Hernandez and William N. Mwangi and Marylene Y. Peroval and Jean-R{\'e}my Sadeyen and Stephanie Ascough and Devanand Balkissoon and Karen A. Staines and Amy K Boyd and John W. McCauley and Adrian D Smith and Colin Butter},
  booktitle={Scientific reports},
  year={2016}
}
Host-genetic control of influenza virus infection has been the object of little attention. In this study we determined that two inbred lines of chicken differing in their genetic background , Lines 0 and C-B12, were respectively relatively resistant and susceptible to infection with the low pathogenicity influenza virus A/Turkey/England/647/77 as defined by substantial differences in viral shedding trajectories. Resistant birds, although infected, were unable to transmit virus to contact birds… CONTINUE READING
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