Host genetics, steatosis and insulin resistance among African Americans and Caucasian Americans with hepatitis C virus genotype-1 infection.

@article{Iuliano2009HostGS,
  title={Host genetics, steatosis and insulin resistance among African Americans and Caucasian Americans with hepatitis C virus genotype-1 infection.},
  author={Angela Danielle Iuliano and Eleanor Feingold and Abdus S Wahed and David E Kleiner and Steven H. Belle and Hari S. Conjeevaram and Joseph Zmuda and Tehming Liang and Leland Jonathan Yee},
  journal={Intervirology},
  year={2009},
  volume={52 1},
  pages={49-56}
}
Hepatic steatosis is the accumulation of fat in liver cells. Insulin resistance (IR) occurs when normal amounts of insulin do not stimulate insulin activity in cells. Both conditions have been described in hepatitis C virus (HCV) infection and are thought to be biologically related. This study examined the association of genetic variants with steatosis and IR among 167 African Americans and 184 Caucasian Americans with HCV genotype-1. Steatosis was defined as at least 5% of fat in cells on… CONTINUE READING

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