Host genes associated with HIV/AIDS: advances in gene discovery.

  title={Host genes associated with HIV/AIDS: advances in gene discovery.},
  author={Ping Nicole An and Cheryl A. Winkler},
  journal={Trends in genetics : TIG},
  volume={26 3},
Twenty-five years after the discovery of HIV as the cause of AIDS there is still no effective vaccine and no cure for this disease. HIV susceptibility shows a substantial degree of individual heterogeneity, much of which can be conferred by host genetic variation. In an effort to discover host factors required for HIV replication, identify crucial pathogenic pathways, and reveal the full armament of host defenses, there has been a shift from candidate-gene studies to unbiased genome-wide… CONTINUE READING
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