Host gene expression profiling in pathogen-host interactions.

  title={Host gene expression profiling in pathogen-host interactions.},
  author={Hamid Hossain and Svetlin Tchatalbachev and Trinad Chakraborty},
  journal={Current opinion in immunology},
  volume={18 4},
Microarray technology is a powerful high-throughput tool for the analysis of host-pathogen interactions that permits simultaneous interrogation of the transcriptional status of thousands of genes. Emerging topics from microarray-based studies employing diverse pathogens and cell types suggest an initial common host response largely characterised by features of the innate immune response. However, specific host gene expression patterns that reflect differences between bacteria of related genera… CONTINUE READING

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