Host gene–microbiome interactions: molecular mechanisms in inflammatory bowel disease

@inproceedings{Chu2017HostGI,
  title={Host gene–microbiome interactions: molecular mechanisms in inflammatory bowel disease},
  author={Hiutung Chu},
  booktitle={Genome Medicine},
  year={2017}
}
Recent studies have identified links between host genetic variants and microbial recognition of the microbiome. Defects in host–microbiome interactions in individuals harboring inflammatory bowel disease risk alleles may result in imbalances of the microbial community, impaired pathogen clearance, and failure to sense beneficial commensal microbes. These… CONTINUE READING