Host factors affecting the outcome of treatment of hepatitis C.

@article{Bruno2004HostFA,
  title={Host factors affecting the outcome of treatment of hepatitis C.},
  author={Raffaele Bruno and Paolo Sacchi and Laura Maiocchi and Cristina Zocchetti and Gaetano Filice},
  journal={Reviews in gastroenterological disorders},
  year={2004},
  volume={4 Suppl 1},
  pages={S3-7}
}
The development of peginterferon and ribavirin combination therapy has significantly improved the sustained virologic response (SVR) rates in patients with chronic hepatitis C. However, poor patient adherence to therapy negatively influences drug levels and drug exposure, often preventing the development of an inhibitory drug level. To optimize patient adherence, the clinician must recognize factors predicting low adherence and negotiate a treatment plan that the patient understands and to… CONTINUE READING

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