Host defense function of the airway epithelium in health and disease: clinical background.

@article{Message2004HostDF,
  title={Host defense function of the airway epithelium in health and disease: clinical background.},
  author={Simon D. Message and Sebastian L Johnston},
  journal={Journal of leukocyte biology},
  year={2004},
  volume={75 1},
  pages={5-17}
}
Respiratory infection is extremely common and a major cause of morbidity and mortality worldwide. The airway epithelium has an important role in host defense against infection and this is illustrated in this review by considering infection by respiratory viruses. In patients with asthma or chronic obstructive pulmonary disease, respiratory viruses are a common trigger of exacerbations. Rhinoviruses (RV) are the most common virus type detected. Knowledge of the immunopathogenesis of such RV… CONTINUE READING

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