Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance.

@article{Apponyi2004HostdefencePO,
  title={Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance.},
  author={Margit A Apponyi and Tara L. Pukala and Craig S Brinkworth and Vita M Maselli and John H. Bowie and M ichael J. Tyler and Grant W. Booker and J. C. Wallace and John A Carver and Frances Separovic and Jason P. Doyle and Lyndon E. Llewellyn},
  journal={Peptides},
  year={2004},
  volume={25 6},
  pages={1035-54}
}
Host-defence peptides secreted from the skin glands of Australian frogs and toads, are, with a few notable exceptions, different from those produced by anurans elsewhere. This review summarizes the current knowledge of the following classes of peptide isolated and characterized from Australian anurans: neuropeptides (including smooth muscle active peptides, and peptides that inhibit the production of nitric oxide from neuronal nitric oxide synthase), antimicrobial and anticancer active peptides… CONTINUE READING