Host co-factors of the retrovirus-like transposon Ty1

  title={Host co-factors of the retrovirus-like transposon Ty1},
  author={Jenni K Risler and Alison E. Kenny and Ryan J Palumbo and Eric R. Gamache and M Joan Curcio},
  booktitle={Mobile DNA},
Long-terminal repeat (LTR) retrotransposons have complex modes of mobility involving reverse transcription of their RNA genomes in cytoplasmic virus-like particles (VLPs) and integration of the cDNA copies into the host genome. The limited coding capacity of retrotransposons necessitates an extensive reliance on host co-factors; however, it has been challenging to identify co-factors that are required for endogenous retrotransposon mobility because retrotransposition is such a rare event. To… CONTINUE READING
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