Host cell surface sialic acid residues are involved on the process of penetration of Toxoplasma gondii into mammalian cells.

@article{Monteiro1998HostCS,
  title={Host cell surface sialic acid residues are involved on the process of penetration of Toxoplasma gondii into mammalian cells.},
  author={Ver{\^o}nica Gomes Monteiro and Christiane Pienna Soares and Wanderley de Souza},
  journal={FEMS microbiology letters},
  year={1998},
  volume={164 2},
  pages={323-7}
}
Tachyzoites of Toxoplasma gondii are able to infect several cell types tested (wild-type chinese hamster ovary (CHO) cells and glycosylation mutants, Vero and LLCMK2 cells). However, the extent of infection varied. Mutant cells which present few or no surface-exposed sialic acid residues were infected to a lower extent. Similar results were obtained if sialic acid residues were removed by previous neuraminidase treatment. Addition of sialic acid residues to surface-exposed glycoconjugates using… CONTINUE READING