Host cell invasion by Trypanosoma cruzi: role of cell surface galactose residues.

@article{Villalta1984HostCI,
  title={Host cell invasion by Trypanosoma cruzi: role of cell surface galactose residues.},
  author={Fernando Villalta and Felipe Kierszenbaum},
  journal={Biochemical and biophysical research communications},
  year={1984},
  volume={119 1},
  pages={
          228-35
        }
}
Alpha-galactosidase treatment of blood, insect and intracellular forms of T. cruzi enhanced their ability to associate with mouse peritoneal macrophages or rat heart myoblasts as evidenced by significant increases in both the percentage of infected cells and the number of parasites per cell. The magnitude of the enhancement was greater with invasive (blood and insect) than with noninvasive (intracellular) forms of the parasite. The enzyme effect was reversible, attaining total recovery in 2.5… CONTINUE READING

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