Host Range Restriction of Insect-Specific Flaviviruses Occurs at Several Levels of the Viral Life Cycle

@inproceedings{Junglen2017HostRR,
  title={Host Range Restriction of Insect-Specific Flaviviruses Occurs at Several Levels of the Viral Life Cycle},
  author={Sandra Junglen and Marvin Korries and Wolfgang Grasse and Janett Wieseler and Anne Kopp and Kyra Hermanns and Moises Le{\'o}n-Ju{\'a}rez and Christian Drosten and Beate Mareike K{\"u}mmerer},
  booktitle={mSphere},
  year={2017}
}
The genus Flavivirus contains emerging arthropod-borne viruses (arboviruses) infecting vertebrates, as well as insect-specific viruses (ISVs) (i.e., viruses whose host range is restricted to insects). ISVs are evolutionary precursors to arboviruses. Knowledge of the nature of the ISV infection block in vertebrates could identify functions necessary for the expansion of the host range toward vertebrates. Mapping of host restrictions by complementation of ISV and arbovirus genome functions could… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 11 times over the past 90 days. VIEW TWEETS
5 Extracted Citations
57 Extracted References
Similar Papers

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 57 references

- deficient human cells

  • M Garcia-Moreno, MA Sanz, L Carrasco
  • 2016

Similar Papers

Loading similar papers…