Host Phylogeny Determines Viral Persistence and Replication in Novel Hosts

  title={Host Phylogeny Determines Viral Persistence and Replication in Novel Hosts},
  author={Ben Longdon and Jarrod D Hadfield and Claire L. Webster and Darren J Obbard and Francis M. Jiggins},
  booktitle={PLoS pathogens},
Pathogens switching to new hosts can result in the emergence of new infectious diseases, and determining which species are likely to be sources of such host shifts is essential to understanding disease threats to both humans and wildlife. However, the factors that determine whether a pathogen can infect a novel host are poorly understood. We have examined the ability of three host-specific RNA-viruses (Drosophila sigma viruses from the family Rhabdoviridae) to persist and replicate in 51… CONTINUE READING
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