Host-Gut Microbiota Metabolic Interactions

  title={Host-Gut Microbiota Metabolic Interactions},
  author={Jeremy K. Nicholson and Elaine Holmes and James Macalister Kinross and R{\'e}my Burcelin and Glenn R. Gibson and Wei Jia and Sven Pettersson},
  pages={1262 - 1267}
The composition and activity of the gut microbiota codevelop with the host from birth and is subject to a complex interplay that depends on the host genome, nutrition, and life-style. The gut microbiota is involved in the regulation of multiple host metabolic pathways, giving rise to interactive host-microbiota metabolic, signaling, and immune-inflammatory axes that physiologically connect the gut, liver, muscle, and brain. A deeper understanding of these axes is a prerequisite for optimizing… 

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