Host Genomics in Infectious Diseases

@inproceedings{Loeb2013HostGI,
  title={Host Genomics in Infectious Diseases},
  author={Mark Loeb},
  booktitle={Infection & chemotherapy},
  year={2013}
}
Understanding mechanisms by which genetic variants predispose to complications of infectious diseases can lead to important benefits including the development of biomarkers to prioritize vaccination or prophylactic therapy. Family studies, candidate genes in animal models, and the absence of well-defined risks where the complications are rare all can point to genetic predisposition. The most common approach to assessing genetic risk is to conduct an association study, which is a case control… CONTINUE READING

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