Host-Defense Peptides with Therapeutic Potential from Skin Secretions of Frogs from the Family Pipidae

@article{Conlon2014HostDefensePW,
  title={Host-Defense Peptides with Therapeutic Potential from Skin Secretions of Frogs from the Family Pipidae},
  author={J. Conlon and M. Mechkarska},
  journal={Pharmaceuticals},
  year={2014},
  volume={7},
  pages={58 - 77}
}
  • J. Conlon, M. Mechkarska
  • Published 2014
  • Medicine, Biology
  • Pharmaceuticals
  • Skin secretions from frogs belonging to the genera Xenopus, Silurana, Hymenochirus, and Pseudhymenochirus in the family Pipidae are a rich source of host-defense peptides with varying degrees of antimicrobial activities and cytotoxicities to mammalian cells. Magainin, peptide glycine-leucine-amide (PGLa), caerulein-precursor fragment (CPF), and xenopsin-precursor fragment (XPF) peptides have been isolated from norepinephrine-stimulated skin secretions from several species of Xenopus and… CONTINUE READING
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