Host-Defense Peptides with Therapeutic Potential from Skin Secretions of Frogs from the Family Pipidae

@inproceedings{Conlon2014HostDefensePW,
  title={Host-Defense Peptides with Therapeutic Potential from Skin Secretions of Frogs from the Family Pipidae},
  author={J Michael Conlon and Milena Mechkarska},
  booktitle={Pharmaceuticals},
  year={2014}
}
Skin secretions from frogs belonging to the genera Xenopus, Silurana, Hymenochirus, and Pseudhymenochirus in the family Pipidae are a rich source of host-defense peptides with varying degrees of antimicrobial activities and cytotoxicities to mammalian cells. Magainin, peptide glycine-leucine-amide (PGLa), caerulein-precursor fragment (CPF), and xenopsin-precursor fragment (XPF) peptides have been isolated from norepinephrine-stimulated skin secretions from several species of Xenopus and… CONTINUE READING