Host Defense Functions of Pulmonary Surfactant

@article{Wright2004HostDF,
  title={Host Defense Functions of Pulmonary Surfactant},
  author={Jo Rae Wright},
  journal={Neonatology},
  year={2004},
  volume={85},
  pages={326 - 332}
}
  • J. Wright
  • Published 1 June 2004
  • Biology
  • Neonatology
Surfactant is a complex of lipids and proteins that reduces surface tension at the air/liquid interface of the lung and regulates immune cell function. Surfactant immune function is primarily attributed to two proteins: SP-A and SP-D. SP-A and SP-D are members of a protein family known as ‘collectins’, which are distinguished by their N-terminal collagen-like region and their C-terminal lectin domain. The lectin domain binds preferentially to sugars on the surface of pathogens and thereby… 

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