Host-Bacterial Mutualism in the Human Intestine

@article{Bckhed2005HostBacterialMI,
  title={Host-Bacterial Mutualism in the Human Intestine},
  author={Fredrik B{\"a}ckhed and Ruth E. Ley and Justin Laine Sonnenburg and Daniel A Peterson and Jeffrey I. Gordon},
  journal={Science},
  year={2005},
  volume={307},
  pages={1915 - 1920}
}
The distal human intestine represents an anaerobic bioreactor programmed with an enormous population of bacteria, dominated by relatively few divisions that are highly diverse at the strain/subspecies level. This microbiota and its collective genomes (microbiome) provide us with genetic and metabolic attributes we have not been required to evolve on our own, including the ability to harvest otherwise inaccessible nutrients. New studies are revealing how the gut microbiota has coevolved with us… 
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