Host–guest encapsulation of materials by assembled virus protein cages

@article{Douglas1998HostguestEO,
  title={Host–guest encapsulation of materials by assembled virus protein cages},
  author={Trevor Douglas and Mark Mingyi Young},
  journal={Nature},
  year={1998},
  volume={393},
  pages={152-155}
}
Self-assembled cage structures of nanometre dimensions can be used as constrained environments for the preparation of nanostructured materials, and the encapsulation of guest molecules, with potential applications in drug delivery and catalysis. In synthetic systems the number of subunits contributing to cage structures is typically rather small,. But the protein coats of viruses (virions) commonly comprise hundreds of subunits that self-assemble into a cage for transporting viral nucleic acids… CONTINUE READING

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