Host–guest encapsulation of materials by assembled virus protein cages
@article{Douglas1998HostguestEO, title={Host–guest encapsulation of materials by assembled virus protein cages}, author={T. Douglas and M. Young}, journal={Nature}, year={1998}, volume={393}, pages={152-155} }
Self-assembled cage structures of nanometre dimensions can be used as constrained environments for the preparation of nanostructured materials, and the encapsulation of guest molecules, with potential applications in drug delivery and catalysis. In synthetic systems the number of subunits contributing to cage structures is typically rather small,. But the protein coats of viruses (virions) commonly comprise hundreds of subunits that self-assemble into a cage for transporting viral nucleic acids… CONTINUE READING
716 Citations
Encapsulation of nanoparticles in virus protein shells.
- Chemistry, Medicine
- Methods in molecular biology
- 2015
- 10
A self-assembled [Fe(II)12L12] capsule with an icosahedral framework.
- Chemistry, Medicine
- Angewandte Chemie
- 2013
- 51
Biomedical and Catalytic Opportunities of Virus-Like Particles in Nanotechnology.
- Biology, Medicine
- Advances in virus research
- 2017
- 38
Protein cages and synthetic polymers: a fruitful symbiosis for drug delivery applications, bionanotechnology and materials science.
- Materials Science, Medicine
- Chemical Society reviews
- 2016
- 62
Protein cage nanoparticles as secondary building units for the synthesis of 3-dimensional coordination polymers
- Chemistry
- 2010
- 22
- PDF
Viral capsids as self-assembling templates for new materials.
- Materials Science, Medicine
- Progress in molecular biology and translational science
- 2011
- 27
Solution scattering studies on a virus capsid protein as a building block for nanoscale assemblies
- Chemistry
- 2011
- 12
- PDF
Self-assembly and optically triggered disassembly of hierarchical dendron-virus complexes.
- Chemistry, Medicine
- Nature chemistry
- 2010
- 131
References
SHOWING 1-10 OF 45 REFERENCES
Acceleration of a Diels–Alder reaction by a self-assembled molecular capsule
- Chemistry, Medicine
- Nature
- 1997
- 351
Quasi-equivalent viruses: a paradigm for protein assemblies.
- Biology, Medicine
- Journal of molecular biology
- 1997
- 259
Quantum Confinement and Host/Guest Chemistry: Probing a New Dimension
- Chemistry, Medicine
- Science
- 1990
- 472
Structures of the native and swollen forms of cowpea chlorotic mottle virus determined by X-ray crystallography and cryo-electron microscopy.
- Biology, Medicine
- Structure
- 1995
- 576
- PDF
Solution conformation of a peptide fragment representing a proposed RNA-binding site of a viral coat protein studied by two-dimensional NMR.
- Chemistry, Medicine
- Biochemistry
- 1991
- 17