Hospital-Acquired Anemia: A Contemporary Review of Etiologies and Prevention Strategies

  title={Hospital-Acquired Anemia: A Contemporary Review of Etiologies and Prevention Strategies},
  author={Niels Douglas Martin and Dane R. Scantling},
  journal={Journal of Infusion Nursing},
Advances in medicine have significantly improved lives and life spans globally. However, these practices have come with their own set of secondary consequences. Hospital-acquired anemia is one such consequence and is conferred by new medicines, operations, procedures, and tests. In this review, the authors will explore the data on this poorly considered phenomenon and discuss the etiologies, outcomes, and prevention strategies for some of the more prolific causes of hospital-acquired anemia… 

Incidence, Predictors, and Outcomes of Hospital‐Acquired Anemia

Severe HAA is associated with increased odds for 30‐day mortality and readmission after discharge; however, it is uncertain whether severe H AA is preventable.

Correlation between Phlebotomy Blood Loss and Hospital- Acquired Anemia among Acute Coronary Syndrome Patients

Future HAA prevention efforts are recommended to be effective if they include multimodal interventions that both decrease unnecessary phlebotomy blood loss through puncturing and bleeding and no significant correlation between HAA and gender & length of hospital stay is identified.

Anemia in hospitalized patients: an overlooked risk in medical care

This study investigated the association between nadir anemia and mortality and length of stay (LOS) in a general population of hospitalized patients.

Transfusion-related Acute Lung Injury in the Perioperative Patient.

Anesthesiologists need to consider transfusion-related acute lung injury in the perioperative setting, identify at-risk patients, recognize early signs of transfusions-related severe lung injury, and have established strategies for its prevention and treatment.



Anemia in critical illness: insights into etiology, consequences, and management.

Normal red blood cell physiology; etiologies of anemia in the intensive care unit; its association with adverse outcomes; and the risks, benefits, and efficacy of various management strategies, including blood transfusion, erythropoietin, blood substitutes, iron therapy, and minimization of diagnostic phlebotomy are reviewed.

Efficacy of red blood cell transfusion in the critically ill: A systematic review of the literature*

In adult, intensive care unit, trauma, and surgical patients, RBC transfusions are associated with increased morbidity and mortality and therefore, current transfusion practices may require reevaluation.

Update in critical care for the nephrologist: transfusion in nonhemorrhaging critically ill patients.

Strong evidence exists that a hemoglobin threshold of less than 7 g/dL conserves resources and may improve outcomes in critically ill patients and that platelet counts greater than 10,000/μL are well tolerated.

Anemia, bleeding, and blood transfusion in the intensive care unit: causes, risks, costs, and new strategies.

  • M. McEvoyA. Shander
  • Medicine
    American journal of critical care : an official publication, American Association of Critical-Care Nurses
  • 2013
The types and causes of anemia, the increased health care utilization and costs associated with anemia and undetected internal bleeding, and the potential benefits and risks associated with transfusion of red blood cells also are explored.

Immune hemolytic anemia caused by drugs

  • G. Garratty
  • Medicine, Biology
    Expert opinion on drug safety
  • 2012
DIIHA is often poorly investigated and many reports do not provide data to support the diagnosis, so it is important to exclude DIIHA in such patients as the only treatment needed is to discontinue the drug.

Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.

Data from the head-to-head trials suggest an advantage of aprotinin over the lysine analogues TXA and EACA in terms of reducing perioperative blood loss, but the differences were small.

Incidence, Correlates, and Outcomes of Acute, Hospital-Acquired Anemia in Patients With Acute Myocardial Infarction

HAA develops in nearly half of acute myocardial infarction hospitalizations among patients treated medically or with percutaneous coronary intervention, commonly in the absence of documented bleeding, and is associated with worse mortality and health status.

Diagnostic blood loss from phlebotomy and hospital-acquired anemia during acute myocardial infarction.

Blood loss from greater use of phlebotomy is independently associated with the development of hospital-acquired anemia during acute myocardial infarction, suggesting that HAA may be preventable by implementing strategies to limit blood loss from laboratory testing.